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What is Vaccine-Derived Polio?

Context: Recently, a case of vaccine-derived polio was confirmed in a two-year-old child from Tikrikilla, Meghalaya. Health authorities clarified that this is not wild poliovirus but an infection seen in individuals with low immunity.

Vaccine Derived Polio

  • It is an uncommon condition that can happen when the weakened virus in the oral polio vaccine changes and becomes strong enough to cause paralysis again.
  • The oral polio vaccine (OPV) contains a live, weakened virus that helps the body build immunity to protect against polio.
  • After vaccination, the weakened virus is excreted in the stool. In areas with poor sanitation and low immunisation coverage, this virus can spread to others in the community.
Polio Virus
  • Polio is a viral infectious disease that can cause irreversible paralysis and even death by affecting the nervous system.
  • Transmission: The virus primarily spreads through the faecal-oral route and can multiply in the intestine, where it can invade the nervous system.
    • It mainly affects children under five.
  • Vaccines:
    • Oral Polio Vaccine (OPV): Administered as a birth dose, followed by three primary doses at 6, 10, and 14 weeks, and a booster dose at 16-24 months.
    • Injectable Polio Vaccine (IPV): This vaccine is given as an additional dose along with the third DPT (Diphtheria, Pertussis, and Tetanus) vaccine under the Universal Immunization Programme (UIP).
  • India was declared polio-free by the World Health Organization (WHO) in 2014, with the last wild poliovirus case reported in 2011.

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