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India Releases Compilation of 10,000 Human Genomes from 83 Population Groups

Context: The Genome India Project has achieved a significant milestone by compiling a database of 10,000 human genomes from 83 population groups, representing about 2% of India’s 4,600 population groups.

About Genome India Project

  • Genome India Project is a government-led initiative launched in 2019 that aims to sequence the genomes of over 10,000 Indians from diverse socio-economic, geographical and linguistic backgrounds to create a comprehensive genomic database of the Indian population.
  • The project involves about 20 institutions across India and with analysis and coordination done by the Centre for Brain Research at IISc, Bangalore.
  • Privacy Measures: Data is anonymized with numeric codes, and access requires proposals vetted by an independent panel.

Genome India Database

  • Housed at the Indian Biological Data Centre (IBDC) in Faridabad, Haryana.
  • Open to global researchers adhering to data-sharing and privacy policies.

Significance

  • Expected to facilitate precision medicine for better healthcare outcomes.
  • Enables targeted clinical interventions based on India’s unique genetic diversity.
  • Opens doors to developing a biotechnology-based economy and manufacturing.

Other Initiatives for Genome Sequencing

IndiGen Programme

  • It aims to undertake whole genome sequencing of thousands of individuals representing diverse ethnic groups from India.
  • Objective: To enable genetic epidemiology and develop public health technologies applications using population genome data.

One Day One Genome Initiative

  • Launched by: the Department of Biotechnology (DBT) and Biotechnology Research and Innovation Council (BRIC)
  • The initiative will highlight the unique bacterial species found in India and emphasise their critical roles in the environment, agriculture and human health.

Check here in Detail: One Day One Genome Initiative

Related Information
  • Genome Sequencing:
    • It is the process of determining the complete DNA sequence of an organism’s genome.
    • It involves reading the order of nucleotide bases (adenine, guanine, cytosine, and thymine) that make up the DNA molecules in an organism’s genome.
  • Genome v/s Gene: The genome is the entire set of genetic material or DNA, while a gene is a specific segment of DNA that codes for a particular protein or RNA molecule.

Genome Sequencing1

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